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10.1126_science.abc4787 | RES EARCH
CORRELATED ELECTRONS
Observation of a critical charge mode in a
strange metal
Hisao Kobayashi1,2*, Yui Sakaguchi1, Hayato Kitagawa1,2, Momoko Oura1,2, Shugo Ikeda1,2,
Kentaro Kuga3, Shintaro Suzuki3, Satoru Nakatsuji3,4,5,6*, Ryo Masuda2,7,8, Yasuhiro Kobayashi2,7,
Makoto Seto2,7, Yoshitaka Yoda9, Kenji Ta... |
10.1126_science.abc8372 | RES EARCH
SUPERCONDUCTIVITY
Restored strange metal phase through suppression of
charge density waves in underdoped YBa2Cu3O7–d
Eric Wahlberg1, Riccardo Arpaia1,2*, Götz Seibold3, Matteo Rossi2†, Roberto Fumagalli2,
Edoardo Trabaldo1, Nicholas B. Brookes4, Lucio Braicovich2,4, Sergio Caprara5,6, Ulf Gran7,
Giacomo Gh... |
10.1126_science.abc5667 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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STRUCTURAL BIOLOGY
Structural basis of antagonizing the vitamin K
catalytic cycle for anticoagulation
Shixuan Liu, Shuang Li, Guomin Shen, Narayanasami Sukumar, Andrzej M. Krezel, Weikai Li*
INTRODUCTION: Vitamin K antagonists (VKAs),
such as warfarin, are o... |
10.1126_science.abe9124 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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IMMUNOLOGY
Canonical T cell receptor docking on peptide–MHC
is essential for T cell signaling
Pirooz Zareie, Christopher Szeto†, Carine Farenc, Sachith D. Gunasinghe, Elizabeth M. Kolawole,
Angela Nguyen, Chantelle Blyth, Xavier Y. X. Sng, Jasmine Li, Claerwe... |
10.1126_science.abd2638 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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HIV
Recapitulation of HIV-1 Env-antibody coevolution in
macaques leading to neutralization breadth
Ryan S. Roark*, Hui Li*, Wilton B. Williams*, Hema Chug*, Rosemarie D. Mason*, Jason Gorman*,
Shuyi Wang, Fang-Hua Lee, Juliette Rando, Mattia Bonsignori, Kwan-... |
10.1126_science.abe0511 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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BACTERIAL PHYLOGENY
A rooted phylogeny resolves early bacterial evolution
Gareth A. Coleman†, Adrián A. Davín†, Tara A. Mahendrarajah, Lénárd L. Szánthó, Anja Spang,
Philip Hugenholtz‡*, Gergely J. Szöllősi‡*, Tom A. Williams‡*
INTRODUCTION: Bacteria are the... |
10.1126_science.abe5601 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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CRISPR
Toxin-antitoxin RNA pairs safeguard
CRISPR-Cas systems
Ming Li†*, Luyao Gong†, Feiyue Cheng†, Haiying Yu, Dahe Zhao, Rui Wang, Tian Wang,
Shengjie Zhang, Jian Zhou, Sergey A. Shmakov, Eugene V. Koonin, Hua Xiang*
INTRODUCTION: CRISPR-Cas systems effic... |
10.1126_science.abe2424 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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CORONAVIRUS
Transmission heterogeneities, kinetics, and
controllability of SARS-CoV-2
Kaiyuan Sun*†, Wei Wang†, Lidong Gao†, Yan Wang, Kaiwei Luo, Lingshuang Ren, Zhifei Zhan,
Xinghui Chen, Shanlu Zhao, Yiwei Huang, Qianlai Sun, Ziyan Liu, Maria Litvinova,
Ale... |
10.1126_science.abf7470 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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IMMUNOLOGY
Marginal zone B cells acquire dendritic cell
functions by trogocytosis
Patrick Schriek, Alan C. Ching, Nagaraj S. Moily, Jessica Moffat, Lynette Beattie, Thiago M. Steiner,
Laine M. Hosking, Joshua M. Thurman, V. Michael Holers, Satoshi Ishido, Mir... |
10.1126_science.abg4020 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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NEUROSCIENCE
Multiscale representation of very large environments
in the hippocampus of flying bats
Tamir Eliav†, Shir R. Maimon†, Johnatan Aljadeff, Misha Tsodyks, Gily Ginosar,
Liora Las, Nachum Ulanovsky*
INTRODUCTION: Place cells are neurons in the
hippo... |
10.1126_science.abg7071 | RES EARCH
R E S E A R C H A R T I C L E
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MOLECULAR BIOLOGY
Regulation of biomolecular condensates by
interfacial protein clusters
Andrew W. Folkmann1,2†, Andrea Putnam1,2†, Chiu Fan Lee3, Geraldine Seydoux1,2*
Biomolecular condensates are cellular compartments that can form by phase separation in the absence
of ... |
10.1126_science.abc6663 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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CHROMATIN
Regulation of the Dot1 histone H3K79
methyltransferase by histone H4K16 acetylation
Marco Igor Valencia-Sánchez*, Pablo De Ioannes*, Miao Wang*, David M. Truong, Rachel Lee,
Jean-Paul Armache, Jef D. Boeke, Karim-Jean Armache†
ubiquitinated nucleos... |
10.1126_science.abh3209 | RES EARCH
RESPIRATORY ENZYMES
The three-spin intermediate at the O–O cleavage and
proton-pumping junction in heme–Cu oxidases
Anex Jose1, Andrew W. Schaefer1, Antonio C. Roveda Jr.1, Wesley J. Transue1, Sylvia K. Choi2,
Ziqiao Ding2, Robert B. Gennis2, Edward I. Solomon1,3*
Understanding the mechanistic coupling of... |
10.1126_science.abh3629 | RES EARCH
FOREST ECOLOGY
Multidimensional tropical forest recovery
Lourens Poorter1*, Dylan Craven2, Catarina C. Jakovac1,3, Masha T. van der Sande1, Lucy Amissah4,
Frans Bongers1, Robin L. Chazdon5,6, Caroline E. Farrior7, Stephan Kambach8, Jorge A. Meave9,
Rodrigo Muñoz1,9, Natalia Norden10, Nadja Rüger8,11,12, Mi... |
10.1126_science.abf8113 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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MICROBIOLOGY
A human apolipoprotein L with detergent-like
activity kills intracellular pathogens
Ryan G. Gaudet, Shiwei Zhu, Anushka Halder, Bae-Hoon Kim, Clinton J. Bradfield, Shuai Huang,
Dijin Xu, Agnieszka Mamiñska, Thanh Ngoc Nguyen, Michael Lazarou, Erd... |
10.1126_science.abi4506 | RES EARCH
CORONAVIRUS
Chimeric spike mRNA vaccines protect against
Sarbecovirus challenge in mice
David R. Martinez1*, Alexandra Schäfer1, Sarah R. Leist1, Gabriela De la Cruz2, Ande West1,
Elena N. Atochina-Vasserman3, Lisa C. Lindesmith1, Norbert Pardi3, Robert Parks4, Maggie Barr4,
Dapeng Li4, Boyd Yount1, Kevin ... |
10.1126_science.abh2858 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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NEUROSCIENCE
Astrocyte Ca2+-evoked ATP release regulates
myelinated axon excitability and conduction speed
Jonathan Lezmy*, I. Lorena Arancibia-Cárcamo, Tania Quintela-López, Diane L. Sherman,
Peter J. Brophy, David Attwell*
INTRODUCTION: Astrocytes support ... |
10.1126_science.abg0879 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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SPLICEOSOME
Structure of the activated human minor spliceosome
Rui Bai*, Ruixue Wan*†, Lin Wang, Kui Xu, Qiangfeng Zhang, Jianlin Lei, Yigong Shi†
INTRODUCTION: Precursor messenger RNA (pre-
mRNA) splicing, which involves the removal of
noncoding introns and... |
10.1126_science.abi4882 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
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MICROBIOLOGY
Spatial transcriptomics of planktonic and sessile
bacterial populations at single-cell resolution
Daniel Dar, Nina Dar, Long Cai*, Dianne K. Newman*
INTRODUCTION: Microbial populations display
heterogeneous gene expression profiles that
result i... |
10.1126_science.abi8794 | RES EARCH
TOPOLOGICAL MATTER
Probing topological spin liquids on a programmable
quantum simulator
G. Semeghini1, H. Levine1, A. Keesling1,2, S. Ebadi1, T. T. Wang1, D. Bluvstein1, R. Verresen1,
H. Pichler3,4, M. Kalinowski1, R. Samajdar1, A. Omran1,2, S. Sachdev1,5, A. Vishwanath1*,
M. Greiner1*, V. Vuletic´ 6*, M. ... |
10.1126_science.abj2096 | RES EARCH
R E S E A R C H A R T I C L E
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ATTOSECOND SCIENCE
Attosecond coherent electron motion in
Auger-Meitner decay
Siqi Li1,2†, Taran Driver1,3,4†, Philipp Rosenberger1,3,5,6, Elio G. Champenois3, Joseph Duris1,
Andre Al-Haddad7, Vitali Averbukh4, Jonathan C. T. Barnard4, Nora Berrah8, Christoph Bostedt7,9,
P... |
10.1126_science.abi7281 | RES EARCH
R E S E A R C H A R T I C L E
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CARBON CAPTURE
A scalable metal-organic framework as a durable
physisorbent for carbon dioxide capture
Jian-Bin Lin1†, Tai T. T. Nguyen2, Ramanathan Vaidhyanathan1,3, Jake Burner4, Jared M. Taylor1,5,
Hana Durekova4, Farid Akhtar6, Roger K. Mah1,5, Omid Ghaffari-Nik7, Stef... |
10.1126_science.abo7651 | RES EARCH
PEPTIDE SEQUENCING
Real-time dynamic single-molecule protein
sequencing on an integrated semiconductor device
Brian D. Reed1*, Michael J. Meyer1, Valentin Abramzon1, Omer Ad1, Pat Adcock1, Faisal R. Ahmad1,
Gün Alppay1, James A. Ball1, James Beach1, Dominique Belhachemi1, Anthony Bellofiore1,
Michael Bello... |
10.1126_science.abo4940 | RES EARCH
METALLURGY
Machine learning–enabled high-entropy
alloy discovery
Ziyuan Rao1, Po-Yen Tung1,2, Ruiwen Xie3, Ye Wei1*, Hongbin Zhang3, Alberto Ferrari4, T.P.C. Klaver4,
Fritz Körmann1,4, Prithiv Thoudden Sukumar1, Alisson Kwiatkowski da Silva1, Yao Chen1,5,
Zhiming Li1,6, Dirk Ponge1, Jörg Neugebauer1, Olive... |
10.1126_science.abq1218 | RES EARCH
EXPATRIATE SCHOLARS
Has China’s Young Thousand Talents program
been successful in recruiting and nurturing
top-caliber scientists?
Dongbo Shi1*, Weichen Liu2, Yanbo Wang3*
In this study, we examined China’s Young Thousand Talents (YTT) program and evaluated its effectiveness
in recruiting elite expatriate... |
10.1126_science.abo6499 | RES EARCH
ANIMAL MOVEMENT
Behavioral responses of terrestrial mammals
to COVID-19 lockdowns
Marlee A. Tucker1*, Aafke M. Schipper1, Tempe S. F. Adams2, Nina Attias3,4, Tal Avgar5, Natarsha L. Babic6,
Kristin J. Barker7, Guillaume Bastille-Rousseau8, Dominik M. Behr9,10, Jerrold L. Belant11, Dean E. Beyer Jr.11,
Niel... |
10.1126_science.abi9810 | RES EARCH
R E S E A R C H A R T I C L E
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BIOPHYSICS
Live-cell micromanipulation of a genomic locus
reveals interphase chromatin mechanics
Veer I. P. Keizer1,2,3†, Simon Grosse-Holz1,2,4, Maxime Woringer1,2, Laura Zambon1,2,3‡,
Koceila Aizel2§, Maud Bongaerts2, Fanny Delille5, Lorena Kolar-Znika1,2, Vittore F. Sco... |
10.1126_science.abq0595 | RES EARCH
EVOLUTIONARY ECOLOGY
Rapid plant trait evolution can alter coastal wetland
resilience to sea level rise
M. L. Vahsen1*, M. J. Blum2, J. P. Megonigal3, S. J. Emrich2,4, J. R. Holmquist3, B. Stiller1,
K. E. O. Todd-Brown5, J. S. McLachlan1*
Rapid evolution remains a largely unrecognized factor in models tha... |
10.1126_science.abp8948 | RES EARCH
SOLID-STATE PHYSICS
Emergent symmetry in a low-dimensional
superconductor on the edge of Mottness
P. Chudzinski1,2†*, M. Berben3,4†, Xiaofeng Xu5, N. Wakeham6, B. Bernáth3,4, C. Duffy3,4, R. D. H. Hinlopen7,
Yu-Te Hsu3,4, S. Wiedmann3,4, P. Tinnemans4, Rongying Jin8, M. Greenblatt9, N. E. Hussey3,4,7*
Upo... |
10.1126_science.abq5375 | RES EARCH
KONDO INSULATORS
Visualizing the atomic-scale origin of metallic
behavior in Kondo insulators
Harris Pirie1,2, Eric Mascot3, Christian E. Matt1, Yu Liu1, Pengcheng Chen1, M. H. Hamidian1,
Shanta Saha4, Xiangfeng Wang4, Johnpierre Paglione4, Graeme Luke5, David Goldhaber-Gordon6,7,
Cyrus F. Hirjibehedin8,9,... |
10.1126_science.abo1633 | LETTERS
Cite as: H.H. Thorp, Science
10.1126/science.adf8367 (2022).
Editorial Expression of Concern
H. Holden Thorp
Editor-in-Chief
On 15 September 2022, Science published the Research Arti-
cle “Structural basis for strychnine activation of human bitter
taste receptor TAS2R46” by Weixiu Xu et al. (1). The editor... |
10.1126_science.abq3773 | RES EARCH
R E S E A R C H A R T I C L E
◥
CORONAVIRUS
Broadly neutralizing antibodies target the
coronavirus fusion peptide
Cherrelle Dacon1†, Courtney Tucker1,2†, Linghang Peng3†, Chang-Chun D. Lee4†, Ting-Hui Lin4,
Meng Yuan4, Yu Cong5, Lingshu Wang6, Lauren Purser1, Jazmean K. Williams7, Chul-Woo Pyo8,
Ivan Kos... |
10.1126_science.abq6100 | mal state (24, 25). A lack of granular quasipar-
ticles would naїvely be expected to suppress
shot noise, because the flow of a continuous
fluid should have no fluctuations.
Despite their ubiquity, strange metals have
yet to be examined through shot-noise mea-
surements for several technical reasons, and
only a few re... |
10.1126_science.abp9979 | RES EARCH
SUPERCONDUCTIVITY
Superconducting vortices carrying a temperature-
dependent fraction of the flux quantum
Yusuke Iguchi1,2*, Ruby A. Shi1,2,3, Kunihiro Kihou4, Chul-Ho Lee4, Mats Barkman5,
Andrea L. Benfenati5, Vadim Grinenko6, Egor Babaev5, Kathryn A. Moler1,2,3,7
Magnetic field penetrates type-II bulk s... |
10.1126_science.abq6753 | RES EARCH
QUANTUM GASES
Universal scaling of the dynamic BKT transition in
quenched 2D Bose gases
Shinichi Sunami1*, Vijay Pal Singh2,3, David Garrick1, Abel Beregi1, Adam J. Barker1, Kathrin Luksch1,
Elliot Bentine1, Ludwig Mathey4,5, Christopher J. Foot1
The understanding of nonequilibrium dynamics in many-body q... |
10.1126_science.abq7487 | RES EARCH
HUMAN EVOLUTION
Genomic inference of a severe human bottleneck
during the Early to Middle Pleistocene transition
Wangjie Hu1,2†‡, Ziqian Hao3†, Pengyuan Du1,3, Fabio Di Vincenzo4, Giorgio Manzi5, Jialong Cui2,
Yun-Xin Fu6,7, Yi-Hsuan Pan2*, Haipeng Li1,8*
Population size history is essential for studying ... |
10.1126_science.abq7768 | RES EARCH
CONSERVATION
The value of private properties for the conservation
of biodiversity in the Brazilian Cerrado
Paulo De Marco Jr.1*, Rodrigo A. de Souza2, André F. A. Andrade1, Sara Villén-Pérez3,
Caroline Corrêa Nóbrega4, Luiza Motta Campello5, Marcellus Caldas6
Areas set aside for conservation within privat... |
10.1126_science.abq6948 | RES EARCH
NANORIBBONS
Topologically localized excitons in single
graphene nanoribbons
Song Jiang1*, Tomáš Neuman1,2, Alex Boeglin1, Fabrice Scheurer1, Guillaume Schull1*
Intrinsic optoelectronic properties of atomically precise graphene nanoribbons (GNRs) remain largely
unexplored because of luminescence quenching ... |
10.1126_science.adc9487 | RES EARCH
MAGNETISM
Proximate deconfined quantum critical point
in SrCu2(BO3)2
Yi Cui1†, Lu Liu2,3†, Huihang Lin1†, Kai-Hsin Wu4, Wenshan Hong2, Xuefei Liu1, Cong Li1, Ze Hu1,
Ning Xi1, Shiliang Li2,5,6, Rong Yu1,7*, Anders W. Sandvik4,2*, Weiqiang Yu1,7*
The deconfined quantum critical point (DQCP) represents a pa... |
10.1126_science.abq8271 | RES EARCH
COMPUTER NETWORKS
Delocalized photonic deep learning on the internet’s edge
Alexander Sludds1*, Saumil Bandyopadhyay1, Zaijun Chen1†, Zhizhen Zhong2, Jared Cochrane1,3,
Liane Bernstein1, Darius Bunandar1‡, P. Ben Dixon3, Scott A. Hamilton3, Matthew Streshinsky4§,
Ari Novack4§, Tom Baehr-Jones4§, Michael Ho... |
10.1126_science.adc8743 | RES EARCH
ORGANIC CHEMISTRY
Closed-loop optimization of general reaction
conditions for heteroaryl Suzuki-Miyaura coupling
Nicholas H. Angello1,2†, Vandana Rathore1,2†, Wiktor Beker3, Agnieszka Wołos3,4, Edward R. Jira2,5,
Rafał Roszak3,4, Tony C. Wu6,7, Charles M. Schroeder1,2,5,8, Alán Aspuru-Guzik6,7,9,10,11,12,
... |
10.1126_science.abh0474 | RES EARCH
BIOMEDICINE
An autonomously swimming biohybrid fish designed
with human cardiac biophysics
Keel Yong Lee1†, Sung-Jin Park1,2†, David G. Matthews3, Sean L. Kim1, Carlos Antonio Marquez1,
John F. Zimmerman1, Herdeline Ann M. Ardoña1‡§, Andre G. Kleber4,
George V. Lauder3, Kevin Kit Parker1,5,6*
Biohybrid sy... |
10.1126_science.adc9998 | Corrected 16 March 2023. See full text.
RES EARCH
R E S E A R C H A R T I C L E
◥
BIOELECTRONICS
Metabolite-induced in vivo fabrication of
substrate-free organic bioelectronics
Xenofon Strakosas1,2*†, Hanne Biesmans1†, Tobias Abrahamsson1, Karin Hellman2,
Malin Silverå Ejneby1, Mary J. Donahue1, Peter Ekström2, F... |
10.1126_science.add1969 | RES EARCH
QUANTUM SIMULATION
Observation of universal Hall response in strongly
interacting Fermions
T.-W. Zhou1,2, G. Cappellini2,3, D. Tusi3, L. Franchi1, J. Parravicini1,2,3, C. Repellin4, S. Greschner5,
M. Inguscio6,2,3, T. Giamarchi5, M. Filippone7, J. Catani2,3, L. Fallani1,2,3*
The Hall effect, which originat... |
10.1126_science.add1219 | RES EARCH
CYTOKINE SIGNALING
Structural basis of g chain family receptor sharing
at the membrane level
Tiantian Cai1†‡, Rachel Lenoir Capello1†, Xiong Pi1,2, Hao Wu1,2, James J. Chou1*§
Common g chain (gc) cytokine receptors, including interleukin-2 (IL-2), IL-4, IL-7, IL-9, IL-15, and IL-21 receptors,
are activate... |
10.1126_science.add2844 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
BITCOIN
Are cryptocurrencies currencies?
Bitcoin as legal tender in El Salvador
Fernando Alvarez*, David Argente*, Diana Van Patten*
INTRODUCTION: The introduction of digital cur-
rencies is perhaps the most important develop-
ment in monetary economics in t... |
10.1126_science.add4445 | tables S2 and S3)—two with low activity rates
and three with high activity.
Slow descent to ~110 m (duration
21.27 ± 22.7 min)
Beginning their dives at depths varying from
the surface to 60 m, the sharks descended to
~110 m with a gradually decreasing pitch angle
(i.e., pointing increasingly downward) from
0° to −15°... |
10.1126_science.add2915 | RES EARCH
AVIAN ECOLOGY
Agriculture and hot temperatures interactively erode
the nest success of habitat generalist birds across
the United States
Katherine S. Lauck1*†, Alison Ke1†, Elissa M. Olimpi1,2, Daniel Paredes1,3, Kees Hood1,
Thomas Phillips1, William R. L. Anderegg4,5, Daniel S. Karp1
Habitat conversion a... |
10.1126_science.add3672 | RES EARCH
SUPERCONDUCTIVITY
Correlating the charge-transfer gap to the maximum
transition temperature in Bi2Sr2Can-1CunO2n+4+d
Zechao Wang1,2†, Changwei Zou3†, Chengtian Lin4, Xiangyu Luo5, Hongtao Yan5, Chaohui Yin5,
Yong Xu3,6,7, Xingjiang Zhou5, Yayu Wang3,6*, Jing Zhu1,2*
As the number of CuO2 layers, n, in eac... |
10.1126_science.adc9150 | Corrected 23 January 2023. See full text.
RES EARCH
R E S E A R C H A R T I C L E
◥
NANOFLUIDICS
Neuromorphic functions with
a polyelectrolyte-confined fluidic memristor
Tianyi Xiong1,2, Changwei Li1,3, Xiulan He1, Boyang Xie1,2, Jianwei Zong1,2, Yanan Jiang4, Wenjie Ma1,
Fei Wu1, Junjie Fei3, Ping Yu1,2*, Lanqun... |
10.1126_science.add4679 | and are of a continuous-time nature. Stratego
is a game for which little progress has been
achieved by the AI research community be-
cause of the many complex aspects of its struc-
ture. Successes in the game have been limited,
with artificial agents only able to play at a
level comparable to a human amateur [see,
e.g.... |
10.1126_science.add5190 | Corrected 3 October 2023. See full text.
RES EARCH
BIOGEOGRAPHY
Limited climatic space for alternative ecosystem
states in Africa
Steven I. Higgins1*, Timo Conradi1, Laurence M. Kruger2,3, Robert B. O’Hara4, Jasper A. Slingsby3,5,6
One of the foundational premises of ecology is that climate determines ecosystems. ... |
10.1126_science.adc9570 | RES EARCH
VOCALIZATION
Toothed whales use distinct vocal registers for
echolocation and communication
Peter T. Madsen1, Ursula Siebert2, Coen P. H. Elemans3*
Echolocating toothed whales (odontocetes) capture fast-moving prey in dark marine environments,
which critically depends on their ability to generate powerful... |
10.1126_science.add5462 | RES EARCH
HYDROLOGY
Agricultural expansion raises groundwater and
increases flooding in the South American plains
Javier Houspanossian1,2*†, Raul Giménez1,2, Juan I. Whitworth-Hulse1, Marcelo D. Nosetto1,3,
Wlodek Tych4, Peter M. Atkinson4, Mariana C. Rufino4,5, Esteban G. Jobbágy1*†
Regional effects of farming on ... |
10.1126_science.add5649 | manner because widely conserved chitinases
are encoded by both commensal microbes and
mammals, particularly those that consume
chitin (8–13).
Dietary chitin induces gastric distension
and type 2 immune triggering
Chitin activates lung group 2 innate lymphoid
cells (ILC2s) by means of interleukin-25 (IL-25),
IL-33, an... |
10.1126_science.add5787 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
MICROBIOME
Microbial-host-isozyme analyses reveal microbial
DPP4 as a potential antidiabetic target
Kai Wang†, Zhiwei Zhang†, Jing Hang†, Jia Liu†, Fusheng Guo†, Yong Ding, Meng Li, Qixing Nie,
Jun Lin, Yingying Zhuo, Lulu Sun, Xi Luo, Qihang Zhong, Chuan Ye,... |
10.1126_science.add7347 | RES EARCH
CRISPR
RNA-triggered protein cleavage and cell growth
arrest by the type III-E CRISPR nuclease-protease
Kazuki Kato1†, Sae Okazaki1†, Cian Schmitt-Ulms2†, Kaiyi Jiang2,3†, Wenyuan Zhou2,
Junichiro Ishikawa1, Yukari Isayama1, Shungo Adachi4, Tomohiro Nishizawa5, Kira S. Makarova6,
Eugene V. Koonin6, Omar O.... |
10.1126_science.add6575 | RES EARCH
MAGNETISM
Topological kinetic crossover in a nanomagnet array
Xiaoyu Zhang1, Grant Fitez1, Shayaan Subzwari1, Nicholas S. Bingham1†, Ioan-Augustin Chioar1,
Hilal Saglam1, Justin Ramberger3, Chris Leighton3, Cristiano Nisoli2*, Peter Schiffer1,4*
Ergodic kinetics, which are critical to equilibrium thermody... |
10.1126_science.add5574 | RES EARCH
2D MATERIALS
Correlated insulator of excitons in WSe2/WS2
moiré superlattices
Richen Xiong1, Jacob H. Nie1, Samuel L. Brantly1, Patrick Hays2, Renee Sailus2, Kenji Watanabe3,
Takashi Taniguchi4, Sefaattin Tongay2, Chenhao Jin1*
A panoply of unconventional electronic states has been observed in moiré super... |
10.1126_science.add7150 | RES EARCH
NEUROSCIENCE
Orphan receptor GPR158 serves as a metabotropic
glycine receptor: mGlyR
Thibaut Laboute1, Stefano Zucca1, Matthew Holcomb2, Dipak N. Patil1†, Chris Garza2,
Brittany A. Wheatley3, Raktim N. Roy3, Stefano Forli2, Kirill A. Martemyanov1*
Glycine is a major neurotransmitter involved in several fu... |
10.1126_science.abq1414 | RES EARCH
SURFACE CHEMISTRY
Quantum effects in thermal reaction rates at
metal surfaces
Dmitriy Borodin1,2*, Nils Hertl1,2, G. Barratt Park1,2,3, Michael Schwarzer1, Jan Fingerhut1,
Yingqi Wang4, Junxiang Zuo4, Florian Nitz1, Georgios Skoulatakis2, Alexander Kandratsenka2,
Daniel J. Auerbach2, Dirk Schwarzer2, Hua G... |
10.1126_science.add7795 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
ENZYMOLOGY
Visualizing the DNA repair process by a photolyase
at atomic resolution
Manuel Maestre-Reyna*, Po-Hsun Wang, Eriko Nango, Yuhei Hosokawa, Martin Saft, Antonia Furrer,
Cheng-Han Yang, Eka Putra Gusti Ngurah Putu, Wen-Jin Wu, Hans-Joachim Emmerich, N... |
10.1126_science.ade1499 | RES EARCH
ELECTROCHEMISTRY
La- and Mn-doped cobalt spinel oxygen evolution
catalyst for proton exchange membrane electrolysis
Lina Chong1, Guoping Gao2, Jianguo Wen3, Haixia Li2, Haiping Xu1, Zach Green4, Joshua D. Sugar5,
A. Jeremy Kropf1, Wenqian Xu6, Xiao-Min Lin3, Hui Xu4, Lin-Wang Wang2, Di-Jia Liu1,7*
Discove... |
10.1126_science.abq1416 | RES EARCH
R E S E A R C H A R T I C L E
◥
ENZYME EVOLUTION
Evolution of increased complexity and specificity at
the dawn of form I Rubiscos
Luca Schulz1, Zhijun Guo2, Jan Zarzycki1, Wieland Steinchen3,4, Jan M. Schuller3,4,
Thomas Heimerl3,5, Simone Prinz6, Oliver Mueller-Cajar2, Tobias J. Erb1,3*, Georg K. A. Hoc... |
10.1126_science.ade0004 | RES EARCH
CONVERGENT EVOLUTION
High level of novelty under the hood
of convergent evolution
Steven M. Van Belleghem1,2*, Angelo A. Ruggieri1, Carolina Concha1,3, Luca Livraghi3,4,
Laura Hebberecht3,5,6, Edgardo Santiago Rivera1,3,7, James G. Ogilvie3,8, Joseph J. Hanly3,4,
Ian A. Warren6, Silvia Planas9, Yadira Orti... |
10.1126_science.adj7576 | RES EARCH
SPINTRONICS
Observation and control of hybrid
spin-wave–Meissner-current transport modes
M. Borst, P. H. Vree, A. Lowther, A. Teepe, S. Kurdi, I. Bertelli, B. G. Simon,
Y. M. Blanter, T. van der Sar*
Superconductors are materials with zero electrical resistivity and the ability to expel magnetic
fields, w... |
10.1126_science.add8737 | Cite as: C. Fischer et al., Science
10.1126/science.adg2821 (2022).
First release: 20 December 2022
www.science.org
(Page numbers not final at time of first release) 1
RESEARCH ARTICLES
Cite as: C. Fischer et al., Science
10.1126/science.add8737 (2022).
Gradual emergence followed by exponential spread
of the ... |
10.1126_science.ade1702 | RES EARCH
SOCIAL LEARNING
Social signal learning of the waggle dance
in honey bees
Shihao Dong1†, Tao Lin1†, James C. Nieh2*, Ken Tan1*
Honey bees use a complex form of spatial referential communication. Their “waggle dance”
communicates the direction, distance, and quality of a resource to nestmates by encoding ce... |
10.1126_science.ade2038 | RES EARCH
BIOMATERIALS
Deformable hard tissue with high fatigue resistance
in the hinge of bivalve Cristaria plicata
Xiang-Sen Meng1†, Li-Chuan Zhou2,3†, Lei Liu1†, Yin-Bo Zhu2, Yu-Feng Meng1, Dong-Chang Zheng2,
Bo Yang1, Qi-Zhi Rao4, Li-Bo Mao1*, Heng-An Wu2*, Shu-Hong Yu1,5*
The hinge of bivalve shells can sustai... |
10.1126_science.add9884 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
GREEN NUDGES
Reducing single-use cutlery with green nudges:
Evidence from China’s food-delivery industry
Guojun He*, Yuhang Pan, Albert Park, Yasuyuki Sawada, Elaine S. Tan
INTRODUCTION: Plastic waste is a global envi-
ronmental threat that endangers marine ... |
10.1126_science.ade2650 | RES EARCH
BIOPHYSICS
MINFLUX dissects the unimpeded walking of kinesin-1
Jan O. Wirth1†, Lukas Scheiderer1†, Tobias Engelhardt1‡, Johann Engelhardt1,
Jessica Matthias1‡, Stefan W. Hell1,2*
We introduce an interferometric MINFLUX microscope that records protein movements with up to
1.7 nanometer per millisecond spati... |
10.1126_science.ade3232 | RES EARCH
HUBBARD MODEL
The Wiedemann-Franz law in doped Mott insulators
without quasiparticles
Wen O. Wang1,2*, Jixun K. Ding1,2, Yoni Schattner2,3,4, Edwin W. Huang5,6,7,
Brian Moritz2, Thomas P. Devereaux2,8,9*
Many metallic quantum materials display anomalous transport phenomena that defy a Fermi liquid
descrip... |
10.1126_science.abq7361 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
HUMAN FERTILITY
The mechanism of acentrosomal spindle
assembly in human oocytes
Tianyu Wu†, Jie Dong†, Jing Fu†, Yanping Kuang†, Biaobang Chen, Hao Gu, Yuxi Luo, Ruihuan Gu,
Meiling Zhang, Wen Li, Xi Dong, Xiaoxi Sun*, Qing Sang*, Lei Wang*
INTRODUCTION: Spi... |
10.1126_science.abq5209 | RES EARCH
R E S E A R C H A R T I C L E S U M M A R Y
◥
CELL BIOLOGY
Endosomal lipid signaling reshapes the endoplasmic
reticulum to control mitochondrial function
Wonyul Jang, Dmytro Puchkov, Paula Samsó, YongTian Liang, Michal Nadler-Holly, Stephan J. Sigrist,
Ulrich Kintscher, Fan Liu, Kamel Mamchaoui, Vincent ... |
10.1126_science.ade3535 | RES EARCH
CARBON OFFSETS
Corrected 31 January 2024. See full text.
Action needed to make carbon offsets from forest
conservation work for climate change mitigation
Thales A. P. West1,2*, Sven Wunder3,4, Erin O. Sills5, Jan Börner6,7, Sami W. Rifai8,
Alexandra N. Neidermeier1, Gabriel P. Frey6, Andreas Kontoleon2,9
... |
10.1126_science.add8655 | RES EARCH
R E S E A R C H A R T I C L E
◥
PLANT GENETICS
Dual domestications and origin of traits
in grapevine evolution
Yang Dong1,2†, Shengchang Duan1,2†, Qiuju Xia3†, Zhenchang Liang4†, Xiao Dong1,2†§,
Kristine Margaryan5,6‡, Mirza Musayev7‡, Svitlana Goryslavets8‡, Goran Zdunić9‡,
Pierre-François Bert10‡, Thie... |
10.1126_science.ade3483 | RES EARCH
NEUROMORPHIC CHIPS
Edge learning using a fully integrated neuro-inspired
memristor chip
Wenbin Zhang1†, Peng Yao1†, Bin Gao1*, Qi Liu1, Dong Wu1, Qingtian Zhang1, Yuankun Li1, Qi Qin1,
Jiaming Li1, Zhenhua Zhu2, Yi Cai2, Dabin Wu1, Jianshi Tang1, He Qian1, Yu Wang2, Huaqiang Wu1*
Learning is highly import... |
10.1126_science.ade4970 | RES EARCH
STELLAR ASTROPHYSICS
An observed population of intermediate-mass helium
stars that have been stripped in binaries
M. R. Drout1,2*†, Y. Götberg2*†, B. A. Ludwig1, J. H. Groh3, S. E. de Mink4,5,
A. J. G. O’Grady1,6, N. Smith7
The hydrogen-rich outer layers of massive stars can be removed by interactions wit... |
10.1126_science.ade4985 | RES EARCH
ROBOTICS
Multilegged matter transport: A framework for
locomotion on noisy landscapes
Baxi Chong1,2, Juntao He3, Daniel Soto3, Tianyu Wang3, Daniel Irvine4,
Grigoriy Blekherman4, Daniel I. Goldman1,2,3*
Whereas the transport of matter by wheeled vehicles or legged robots can be guaranteed in engineered
la... |
10.1126_science.ade5156 | RES EARCH
EVOLUTION
Evolutionary transitions from camouflage to
aposematism: Hidden signals play a pivotal role
Karl Loeffler-Henry1†, Changku Kang2,3*†, Thomas N. Sherratt1
The initial evolution of warning signals in unprofitable prey, termed aposematism, is often seen as
a paradox because any new conspicuous muta... |
10.1126_science.ade5050 | RES EARCH
QUANTUM INFORMATION
An atomic-scale multi-qubit platform
Yu Wang1,2†, Yi Chen1,2,3,4†, Hong T. Bui1,5†, Christoph Wolf1,2, Masahiro Haze1,6,
Cristina Mier1,7, Jinkyung Kim1,5, Deung-Jang Choi1,7,8,9, Christopher P. Lutz10,
Yujeong Bae1,5*, Soo-hyon Phark1,2*, Andreas J. Heinrich1,5*
Individual electron sp... |
10.1126_science.ade7471 | RES EARCH
CHEMICAL DYNAMICS
Stereodynamical control of the H + HD → H2 + D
reaction through HD reagent alignment
Yufeng Wang1†, Jiayu Huang1†, Wei Wang1,2, Tianyu Du1,2, Yurun Xie1,3, Yuxin Ma1,2, Chunlei Xiao1,4*,
Zhaojun Zhang1*, Dong H. Zhang1,3,4*, Xueming Yang1,3,4*
Prealigning nonpolar reacting molecules lead... |
10.1126_science.ade7651 | RES EARCH
QUANTUM SIMULATION
A superconducting quantum simulator based
on a photonic-bandgap metamaterial
Xueyue Zhang1,2†, Eunjong Kim1,2†, Daniel K. Mark3, Soonwon Choi3, Oskar Painter1,2,4*
Synthesizing many-body quantum systems with various ranges of interactions facilitates the study of
quantum chaotic dynamic... |
10.1126_science.ade7147 | RES EARCH
CHEMISTRY
Modification of ground-state chemical reactivity via
light–matter coherence in infrared cavities
Wonmi Ahn1, Johan F. Triana2, Felipe Recabal2, Felipe Herrera2,3*, Blake S. Simpkins4*
Reaction-rate modifications for chemical processes due to strong coupling between reactant molecular
vibrations ... |
10.1126_science.ade5337 | tion applied—much faster than the timescale
over which the data and spectator qubits de-
correlate. This second requirement has limited
the experimental implementation of such pro-
tocols because a substantial number of mea-
surements are required to reliably estimate
the effects of a dynamic noise environment.
Further... |
10.1126_science.ade6360 | RES EARCH
MPOX
Structure of monkeypox virus DNA
polymerase holoenzyme
Qi Peng1†, Yufeng Xie2†, Lu Kuai1†, Han Wang1,3, Jianxun Qi1, George F. Gao1,2,4,5,6*, Yi Shi1,5,6*
The World Health Organization declared mpox (or monkeypox) a public health emergency of
international concern in July 2022, and prophylactic and t... |
10.1126_science.ade6219 | RES EARCH
R E S E A R C H A R T I C L E
◥
QUANTUM SIMULATION
Observing the quantum topology of light
Jinfeng Deng1†, Hang Dong1†, Chuanyu Zhang1, Yaozu Wu1, Jiale Yuan1, Xuhao Zhu1, Feitong Jin1,
Hekang Li1, Zhen Wang1,2,3, Han Cai1, Chao Song1*, H. Wang1,2,3*, J. Q. You1, Da-Wei Wang1,3,4*
Topological photonics ... |
10.1126_science.ade8654 | RES EARCH
APPLIED PHYSICS
Fiber pumps for wearable fluidic systems
Michael Smith1*, Vito Cacucciolo1,2, Herbert Shea1*
Incorporating pressurized fluidic circuits into textiles can enable muscular support, thermoregulation,
and haptic feedback in a convenient wearable form factor. However, conventional rigid pumps,
... |
10.1126_science.ade8450 | RES EARCH
NANOPHOTONICS
Experimentally realized in situ backpropagation for
deep learning in photonic neural networks
Sunil Pai1*†, Zhanghao Sun1, Tyler W. Hughes2‡, Taewon Park1, Ben Bartlett2†, Ian A. D. Williamson1§,
Momchil Minkov1‡, Maziyar Milanizadeh3, Nathnael Abebe1#, Francesco Morichetti3, Andrea Melloni3,... |
10.1126_science.ade9097 | RES EARCH
R E S E A R C H A R T I C L E
◥
COMPUTER SCIENCE
Human-level play in the game of Diplomacy by
combining language models with strategic reasoning
Meta Fundamental AI Research Diplomacy Team (FAIR)†, Anton Bakhtin1‡, Noam Brown1*‡,
Emily Dinan1*‡, Gabriele Farina1, Colin Flaherty1‡, Daniel Fried1,2, Andrew... |
10.1126_science.ade5671 | RES EARCH
SEXUAL SELECTION
Female preference for rare males is maintained by
indirect selection in Trinidadian guppies
Tomos Potter1*†, Jeff Arendt2†, Ronald D. Bassar3, Beth Watson4, Paul Bentzen4,
Joseph Travis1, David N. Reznick2
When females prefer mates with rare phenotypes, sexual selection can maintain rathe... |
10.1126_science.ade9803 | RES EARCH
CALCULUS INSTRUCTION
Establishing a new standard of care for calculus
using trials with randomized student allocation
Laird Kramer1,2*, Edgar Fuller1,3,4*, Charity Watson1,3,4, Adam Castillo1,3,4†,
Pablo Duran Oliva1,3,5, Geoff Potvin1,2
Calculus, the study of change in processes and systems, serves as th... |
10.1126_science.ade9434 | Corrected 8 August 2023. See full text.
RES EARCH
ENZYME DESIGN
Combinatorial assembly and design of enzymes
R. Lipsh-Sokolik1, O. Khersonsky1, S. P. Schröder2, C. de Boer2†, S.-Y. Hoch1, G. J. Davies3,
H. S. Overkleeft2, S. J. Fleishman1*
The design of structurally diverse enzymes is constrained by long-range int... |
10.1126_science.adf0435 | RES EARCH
NEUROSCIENCE
Psychedelics promote neuroplasticity through
the activation of intracellular 5-HT2A receptors
Maxemiliano V. Vargas1,2, Lee E. Dunlap2,3†, Chunyang Dong4†, Samuel J. Carter2,3,
Robert J. Tombari2,3, Shekib A. Jami5, Lindsay P. Cameron1, Seona D. Patel3, Joseph J. Hennessey6,
Hannah N. Saeger2,... |
10.1126_science.ade9858 | RES EARCH
QUANTUM SENSING
Nanoscale covariance magnetometry with diamond
quantum sensors
Jared Rovny1, Zhiyang Yuan1, Mattias Fitzpatrick1†, Ahmed I. Abdalla1‡, Laura Futamura1§,
Carter Fox2, Matthew Carl Cambria2, Shimon Kolkowitz2, Nathalie P. de Leon1*
Nitrogen vacancy (NV) centers in diamond are atom-scale defe... |
10.1126_science.adf0460 | RES EARCH
R E S E A R C H A R T I C L E
◥
NEUROSCIENCE
Cross-modal representation of identity in the
primate hippocampus
Timothy J. Tyree1,2, Michael Metke1,3, Cory T. Miller1,3*
Faces and voices are the dominant social signals used to recognize individuals among primates. Yet, it
is not known how these signals a... |
10.1126_science.adf0752 | RES EARCH
PLANT SCIENCE
Brassinosteroid coordinates cell layer interactions in
plants via cell wall and tissue mechanics
Robert Kelly-Bellow1*†, Karen Lee1†, Richard Kennaway1, J. Elaine Barclay1, Annabel Whibley1,
Claire Bushell1, Jamie Spooner1, Man Yu1, Paul Brett2, Baldeep Kular2, Shujing Cheng3,
Jinfang Chu3,4,... |
10.1126_science.adf1506 | Corrected 21 August 2023. See full text.
RES EARCH
R E S E A R C H A R T I C L E
◥
TOPOLOGICAL MATTER
Quantum metric nonlinear Hall effect in a topological
antiferromagnetic heterostructure
Anyuan Gao1, Yu-Fei Liu1,2, Jian-Xiang Qiu1, Barun Ghosh3, Thaís V. Trevisan4,5, Yugo Onishi6, Chaowei Hu7,
Tiema Qian7, Hun... |
10.1126_science.adf0895 | RES EARCH
CONSERVATION ECOLOGY
Ecosystem-based management outperforms
species-focused stocking for enhancing fish populations
Johannes Radinger1*†, Sven Matern1,2†, Thomas Klefoth3, Christian Wolter1, Fritz Feldhege1,2,
Christopher T. Monk1,4, Robert Arlinghaus1,2,5
Ecosystem-based management is costly. Therefore, ... |
10.1126_science.ade7759 | RES EARCH
ACTIVE MATTER
Ultrafast reversible self-assembly of living
tangled matter
Vishal P. Patil1†, Harry Tuazon2†, Emily Kaufman2, Tuhin Chakrabortty2, David Qin3,
Jörn Dunkel4*, M. Saad Bhamla2*
Tangled active filaments are ubiquitous in nature, from chromosomal DNA and cilia carpets to root
networks and worm ... |
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